Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

Friday, February 10, 2006

The Council of Australian Governments (COAG) will meet in Canberra today for its first meeting of 2006. Members of COAG are the Prime Minister, State Premiers, Australian Capital and Northern Territory Chief Ministers, and the President of the Australian Local Government Association. COAG is chaired by the Prime Minister.

On the agenda is a wide range of issues such as health, economic reform, regulation, and education.

The state leaders (all of whom are members of the Australian Labor Party), met last night to develop a strategy for dealing with John Howard, Australia’s Prime Minister.

Saturday, March 14, 2009

Rico Daniels is a British TV presenter living in France who is known for his two television series — The Salvager — whilst he still lived in the UK and then Le Salvager after he moved to France. Rico has been in a variety of jobs but his passion is now his profession – he turns unwanted ‘junk’ into unusual pieces of furniture. Rico’s creations and the methods used to fabricate them are the subject of the Salvager shows.

Rico spoke to Wikinews in January about his inspiration and early life, future plans, other hobbies and more. Read on for the full exclusive interview, published for the first time:

Tuesday, November 21, 2006

24 years ago Iraq and Syria severed diplomatic relations because Syria accused Iraq of giving support to the Muslim Brotherhood who were causing disorder in Syria. Now, as an outcome of meetings between Walid Moallem the Syrian Foreign Minister, the Iraqi President Jalal Talabani and Prime Minister Nuri al-Maliki, relations will be restored.

Both countries are agreed that the borders between them should be sealed more tightly to prevent the flow of fighters, arms and ammunition to Iraq, Syria saying that Iraq should do more to secure the border than it has been doing lately.

The two countries are agreed that US troops are needed in Iraq at present but that they should leave as soon as they are no longer needed. Syria wants a timetable for the progressive withdrawal of US forces.

The steps needed to establish full diplomatic relations and to open embassies in Baghdad and Damascus are set out in an agreement signed today in Baghdad. Zebari proclaimed “We will hoist the Iraqi flag in Syria and the Syrian flag in Iraq”.

Meanwhile, President Talabani has agreed to meet Iran’s President Mahmoud Ahmadinejad in Tehran on Saturday to discuss security matters.

Although the British Prime Minister has been encouraging more positive relations between Iraq and its neighbors, Syria and Iran, the United States has been critical of both of them. Last week, US Secretary of State Condoleezza Rice said she was opposed to including Syria and Iran in talks about security in Iraq. She accused Syria of having aligned itself with “the forces of extremism” and expressed frustration that despite repeated talks with Syria, nothing seems to have influenced their behavior. Regarding Iran, she said she could see nothing in its behavior that suggested it could contribute to stability in the area. She expressed the view that Iraq must take more responsibility for its own security.

Today, the White House welcomed the news of the rapprochement between Syria and Iraq. The spokesman for the US National Security Council saying “We’ve always encouraged Iraq’s neighbors to take a role in supporting and assisting the unity government in Iraq”.

President Bush met the Iraq Study Group, headed by former secretary of state James Baker on Monday. The Democrats in the Group said that, in order to encourage the Iraqi government to face its responsibilities, there should be a phased withdrawal of US troops from Iraq, starting now. The President rejected this suggestion, remarking that this was a military matter and depended upon the situation on the ground.

Recommendations from the bi-partisan study Group are expected to be delivered to the President and Congress sometime in December this year. The group is composed of five Democrats and five Republicans.

Monday, September 4, 2006

A gunman has opened fire on tourists in Amman, the capital of Jordan. One Briton was killed and five others were injured at the Roman Theatre in central Amman. Two British women were among the injured tourists, the rest were from the Netherlands, New Zealand and Australia (So far the dead man has not been named). It is not yet clear whether the man was acting on his own or as part of group.

The attack took place at 12:30 local time (09:30 GMT). The lone gunman shouted “God is great” (in Arabic) before firing up to 12 shots, according to eye witness reports given to the AFP news agency. When he ran out of ammunition the man fled the scene but was overpowered by Police and local inhabitants. Interior Minister Eid al-Fayez confirmed that a man was arrested and is now being questioned.

A BBC reporter in the area has said that the area is cordoned and currently being patrolled by armed police.

Wednesday, February 2, 2005

Sydney, Australia –A 16 year old Sydney student was killed when a 10 metre gum tree fell on the tent in which she was sleeping.

Another girl sleeping beside her was unharmed.

The accident occurred at 1:30am AEDT at a campsite near Wombeyan Caves. The girl was participating in an overnight leadership camp with Sydney’s private Queenwood School for Girls.

Severe storms have lashed the east coast of Australia for the past few days.

Saturday, April 16, 2005

The Food and Drug Administration (FDA) has penned a stiff reminder to drug giants Bayer Pharmaceuticals Corp. and GlaxoSmithKline PLC: pull your 15-second “reminder” ad for the erectile dysfunction drug, Levitra, off TV.

FDA said there is no evidence Levitra is better than rival drugs Viagra from Pfizer, or Cialis, owned by Eli Lilly and Co., in producing results that make female partners happy.

Levitra and Cialis together control about 30 per cent of the market for such drugs, but Pfizer takes the majority share.

Reminder ads can only call attention to a drug, not claim it works better, or at all.

“In one of [the ad’s] scenes, the man strokes the woman’s hair and face as she affectionately puts her hand on his wrist,” the FDA wrote. “In the other, she puts her arms around his neck and they embrace.”

“The totality of the TV ad also represents or suggests that Levitra will provide a satisfying sexual experience from the female partner’s perspective,” the agency wrote.

Glaxo spokesman Michael Fleming said the drug makers would comply. Bayer developed Levitra and partnered with Glaxo to market the pills in 2001. Bayer recently turned its part of the promotion over to Schering-Plough Corp.

Shares of Bayer fell 75 cents to $32.96 on Friday. Shares of GlaxoSmithKline rose 32 cents to close at $47.82. Schering-Plough shares rose 8 cents to end at $20.65.

Friday, September 8, 2006

From September 3 to 8, experts gathered at the 10th International Congress on Obesity in Sydney, Australia, to discuss what they call the worldwide “obesity epidemic”. According to the World Health Organization (WHO), 1 billion people in the world today are overweight, and 300 million of those are obese. “Obesity and overweight pose a major risk for serious diet-related chronic diseases, including type 2 diabetes, cardiovascular disease, hypertension and stroke, and certain forms of cancer“, a WHO fact sheet states. According to AP, experts at the conference “have warned that obesity is a bigger threat than AIDS or bird flu, and will easily overwhelm the world’s health care systems if urgent action is not taken”.

Of particular concern is the large number of overweight children. Dr. Stephan Rossner from Sweden’s Karolinska University Hospital, a leading obesity expert who was present at the conference, has warned that as a result of the increasing number of overweight children, “we will have, within a decade or two, a number of young people who are on kidney dialysis. There will not be organs for everybody”. UK-based International Obesity Task Force has said that junk food manufacturers target children, for example, through Internet advertising, chat rooms, text messages, and “advergames” on websites. Politicians are not doing enough to address the problem of obesity, including childhood obesity, the experts said.

According to Wikipedia, examples of junk food include, but are not limited to: hamburgers, pizza, candy, soda, and salty foods like potato chips and french fries. A well-known piece of junk food is the Big Mac. The US version of just one Big Mac burger contains 48% of calories from fat, 47% US Recommended Dietary Allowance (RDA) of fat, 52% RDA of saturated fat, 26% RDA of cholesterol, 42% RDA of sodium, and little nutritional value. It also has 18% of calories from protein. According to WHO, most people need only about 5% calories from protein. Staples such as rice, corn, baked potatoes, pinto beans, as well as fruits and vegetables such as broccoli, cauliflower, zucchini, oranges, and strawberries, provide more than this required amount of protein without the unhealthy amounts of fats or sodium, without cholesterol, and with plenty of fiber, vitamins, and minerals.

Both WHO and the American Centers for Disease Control and Prevention (CDC) define overweight in adults as a Body Mass Index (BMI) of 25 or above, and obese as a BMI of 30 or above. To combat overweight and obesity, WHO recommends that, among other things, people should be taking the following steps

• eating more fruit and vegetables, as well as nuts and whole grains;
• engaging in daily moderate physical activity for at least 30 minutes;
• cutting the amount of fatty, sugary foods in the diet;
• moving from saturated animal-based fats to unsaturated vegetable-oil based fats.

Sunday, March 15, 2009

200,000 litres of oil leaked into waters off the coast of Brisbane from the Pacific Adventurer when their fuel tanks were damaged in rough seas on Wednesday. The figure is about ten times higher than the original estimate of twenty thousand litres of oil. The devastating diesel oil spill has spread along 60 kilometres (37 miles) of the Queensland coast. In addition, 31 containers with 620 tonnes of ammonium nitrate fertiliser flew overboard during the violent storm.

Questions are being asked why the Hong Kong cargo ship was out in seas with nine meter waves caused by Cyclone Hamish, a Category 5 tropical cyclone, as well as why the fertiliser containers were not properly secured. One of the overboard containers ruptured the hull of the Pacific Adventurer, causing between 30 to 100 tonnes of oil to spew from the severely damaged ship.

If the ammonium nitrate mixes with the heavy oil, an explosion could occur. None of the containers have been recovered. Some of these may float, but it is believed that they may have sunk which then may cause algal blooms.

Disaster zones have been declared at Bribie and Moreton Islands, and along the Sunshine coast.

The vessel’s owner, Swire Shipping, reported that a second leak began on Friday, when the ship began listing after docking at Hamilton for repairs. “As full soundings of the vessel’s tanks were being taken at the port to determine how much oil had leaked from the vessel, a small quantity of fuel oil escaped from the Pacific Adventurer,” it stated. The ship was brought upright, and a recovery vessel was used to suck up the oil from the water. The leak produced a 500m-long oil slick down the Brisbane River. Booms were placed around this oil spill so that a skimmer could clean up the second spill.

Swire Shipping could face clean up costs of AU$100,000 a day as well as fines up to AU$1.5million (US$977,000; £703,000) if found guilty of environmental breaches or negligence.

Sunshine Coast beaches are slowly starting to be reopened. The beach of Mooloolaba was still closed following reports of burning sensations from swimmers. 12 beaches remain closed; however, 13 have been reopened.

Over 300 state government and council workers are using buckets, rakes and spades in the clean up effort. Sunshine Coast Mayor Bob Abbott says the majority will be gone by Sunday afternoon. The full environmental impact on wildlife is not yet known. One turtle and seven pelicans have been found covered in oil.

There are concerns that the drinking water of Moreton Island is at risk, as the island uses water from the underground water table near the oil spill site.

“Every bucketload of contaminated sand has to be removed from the island by barge, and each bucketload from a front-end loader weighs about one tonne. It’s just an impossible task,” said Mr Trevor Hassard of the Tangalooma Dolphin Education Centre.

The commercial fishing industry has suffered from the incident. Trawlers won’t resume operations until Sunday evening, and any catches will be tested for human consumption.

Sunday, January 11, 2015

Space transport services company SpaceX launched their fifth Dragon resupply vehicle to the International Space Station yesterday. The spacecraft — containing more than 2,200kg (5,000 pounds) of food, experiments, and spare parts — successfully decoupled from the launch rocket and should reach the station early tomorrow.

The launch was postponed from Tuesday because of a technical issue on the second stage of the rocket. The shipment includes replacements for cargo aboard the spaceship Cygnus, destroyed during a failed launch in October. Cygnus belonged to the rival Orbital Sciences Corporation.

SpaceX tried unsuccessfully to land the Falcon 9 delivery rocket for reuse. The rocket reached an unmanned barge in the Atlantic, but landed too hard. SpaceX CEO Elon Musk said the landing “bodes well for the future, though”. The attempted salvage of the rocket was experimental, using new retractable fins. Next time they will add extra hydraulic fluid, Musk said.

The ship’s support equipment was damaged but, according to Musk, the barge is intact. Last year saw two successful SpaceX splashdowns but landing on such a small target as a ship is unique.